Endocrine Abstracts

Thyroid-stimulating hormone receptor (TSHR) is typically known to be expressed in the thyroid gland of mammals for the control of body metabolism. However, because the TSHR ancestor is the only glycoprotein hormone receptor found in invertebrates, we hypothesized that TSHR evolves much earlier than FSHR and LHR and thus can be expressed in mammalian gonads for certain uncharacterized impacts. To prove this, real-time PCR quantification against Tshr in all male mouse r...